When the termination of the Jewish people started, what was called the "Final Solution," the Nazis were able to observe high up from their windows, onto Umschlagplatz Square. From there the SS oversaw the loading of thousands of Jews onto train cars and to their deaths, towards Treblinka Death Camp.
At the end of the war, the Nazis destroyed the entire Ghetto and its buildings, besides a few buildings used by the Gestapo. This is how this building was not damaged at all, being the headquarters.
Since the war and until now, the building was used as research labs for the University of Warsaw. At the entrance is a sign in memory of the history of the place.